Findings from a recently published, randomized, controlled 2 x 2 factorial study show that less sleep and poor sleep quality are associated with less weight loss. was shown.
Led by Signe S. Torekov, MD, MSc, Professor of Clinical and Translational Metabolism, Covenhounds University, the study included 195 obese adults who completed an 8-week low-calorie diet and maintained weight loss for 1 year were randomly assigned to. Liraglutide 3 mg/day or placebo with or without exercise. Her wrist-worn GENEActiv accelerometer and the Pittsburgh Sleep Quality Index (PSQI) were used to measure sleep duration and quality before and after meal initiation.
Participants randomized to exercise were encouraged to participate in two individually administered 30-minute sessions per week plus two 45-minute supervised sessions per week. . Monitored sessions included interval-based spinning and circuit training. To support weight maintenance after weight loss, all participants attended monthly consultations on weight measurement and dietary support as recommended by Danish authorities. The adult cohort ranged from She 18 to He 65 years and had a body mass index of 32 to 43 kg/m2.2.
A total of 166 (85%) participants participated in the final assessment of body weight 52 weeks after randomization, valid accelerometer data were available for 119 participants, and PSQI global scores were available. Before the low-calorie diet, overall mean sleep time was 6.07 (±0.83) hours/night measured by accelerometer, mean self-reported sleep time was 6.60 (±1.05) hours/night, and self-reported Sleep quality was 6.1 (±3.1), indicating poor sleep quality on average.
After 8 weeks of low-calorie dieting, researchers observed a mean 13.1 kg weight loss (95% CI, 12.4-13.7) and a mean 2.3 point (95% CI, 2.1-2.6) decrease in fat percentage. . Additionally, self-reported sleep duration increased by 9 minutes each night, sleep efficiency increased by 2.1%, PSQI overall score decreased by –0.8 (95% CI, –1.2 to –4.0), and sleep quality improved. is shown.
At randomization, 48 participants were identified as having short sleep duration immediately after diet-induced weight loss. This was defined as an average sleep time of less than 6 hours per night as measured by an accelerometer, and the remaining 111 were considered to have more than 6 hours per night. normal sleep. During the 52-week weight maintenance phase, short sleepers regained weight, whereas normal sleepers maintained weight loss. Linear regression analysis showed that for each hour of her average sleep time after weight loss, the change in weight after 52 weeks was -1.7 kg (P. = .073) Change in body fat percentage is –0.80 points (P. = .026).
The PSQI showed that the difference in weight change during weight maintenance was 1.5 kg (P. = .27) and fat percentage by 0.1 percentage point (P. = .91) favors quality sleepers. Worsening of his PSQI score overall after dietary weight loss tended to be related to weight regain (P. = .052) and increased fat percentage (P. = .087) weight maintenance.
It was also shown that good sleepers, identified before the low-calorie diet, lost significantly more weight (-3.5 kg; P. = .010) and body fat percentage (–1.3 percentage points; P. = .018) over the study period compared with poor sleepers. Furthermore, when assessing the impact of weight loss maintenance with exercise on sleep, the researchers found that the exercise group maintained the self-reported increase in sleep quality from the low-calorie diet at his 52nd week. We observed that the non-exercise group relapsed, whereas the non-exercise group relapsed. The factor that improved with exercise compared to controls was daily disturbance (P. <.001) and perceived sleep quality (P. = .05).