Dietary intervention may improve cardiometabolic health in schizophrenia


December 23, 2022

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A nutritional program focused on increasing prebiotic and probiotic intake improved cardiometabolic health in patients with schizophrenia spectrum disorders, according to a study published in . BMC Psychiatry.

Evidence suggests that patients with psychiatric disorders, especially long-term psychiatric disorders, have higher disability, morbidity, and mortality. All of these can exacerbate the risk of cardiometabolic diseases such as metabolic syndrome. Alfonso Sevillano Jimenez, of Reina Sofia University Hospital, Spain, and colleagues. Although lifestyle changes are not a major focus of clinical practice in this patient population, researchers note that there should probably be more emphasis on dietary interventions, including those that may modulate the gut microbiome. doing.

A nutritional program focused on increasing prebiotic and probiotic intake improved cardiometabolic health in patients with schizophrenia spectrum disorder. Source: Adobe Stock

“In this regard, the use of the term ‘psychobiotics’ is noteworthy, as it refers to a range of probiotics and/or prebiotic substances that provide health benefits to people with psychosis.” they are writing

Using a randomized, double-blind, controlled trial, Sevillano-Jiménez et al. We sought to assess the effects of highly symbiotic diets. Pandemic.

Senior practice nurses developed nutrition education and interventions. Then, for 6 months, patients in the control group received conventional dietary counseling individually. The intervention group established a personalized nutrition education program that included prebiotics and probiotics, such as dairy and fermented foods, green leafy vegetables, high-fiber fruits, and whole grains.

Forty-four patients—21 in the control group and 23 in the intervention group—completed follow-up. A within-group analysis revealed that all anthropometric variables in the intervention group were significantly improved after his 6 months.

Additionally, the intervention group was found to have a 27.4% reduction in the prevalence of metabolic syndrome risk factors. This includes significant reductions in waist circumference, waist circumference, triglycerides and HDL cholesterol. The intervention group also experienced a reduction in diastolic blood pressure. The data showed that the glycemic profile worsened in both study groups, but was less pronounced in the intervention group.

Sevillano-Jiménez et al. pointed out that increasing prebiotic and probiotic intake may be beneficial for cardiometabolic health in patients with schizophrenia spectrum disorder.

“Nursing plays an important role in achieving optimal health outcomes, and through diet and nutrition education, underlies a multimodal approach and lifestyle adjustment,” they wrote, noting that in a larger sample size He added that further research is needed.



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